Cellular- and/or tissue-based products (CTPs) are types of wound dressings or coverings that support wound healing. There are multiple options for these products, including: non-viable cells, tissue-based: animal; non-viable cells, tissue-based: human; viable human cells, cultured in vitro: animal substrate; viable human cells, cultured in vitro: synthetic substrate; and viable human cells, non-cultured: intact tissue.
In January 2026, new Final Rules regarding CTP/skin substitute application are scheduled to go into effect. Please consult your region’s Local Coverage Determination and/or your local payers’ guidelines for specific details on coverage and use specifications. Products listed in WoundSource may or may not be on the covered list under the new guidelines, so it is imperative that readers verify coverage policies, medical necessity requirements, and coding instructions for their desired product(s). See pages [XXX] for full disclaimer information.
Integra® Meshed Dermal Regeneration Template is an advanced bilayer matrix consisting of a porous, three-dimensional dermal replacement layer and a temporary epidermal layer. The dermal replacement layer (collagen and glycosaminoglycan) is designed with a controlled porosity and defined degradation rate to promote neodermal formation. The epidermal layer (pre-meshed polysiloxane) provides a moisture and bacterial barrier.
Integra® Omnigraft™ Dermal Regeneration Matrix is an advanced bilayer matrix for dermal regeneration. The dermal replacement layer consists of a porous, three-dimensional matrix comprised of bovine collagen and chondroitin-6-sulfate that is designed with controlled porosity and defined degradation rate. The temporary epidermal layer is made of a thin silicone layer to provide immediate wound coverage and control moisture loss from the wound.
Integra® PriMatrix® Ag Antimicrobial Dermal Repair Scaffold is a unique scaffold which provides an ideal environment to support cellular repopulation and revascularization processes for the management of the most challenging wounds.
Integra® PriMatrix® Dermal Repair Scaffold is a unique scaffold which provides an ideal environment to support cellular repopulation and revascularization processes for the management of the most challenging wounds.
Integra® Wound Matrix is an advanced wound care device consisting of a porous, three-dimensional dermal layer comprised of collagen and glycosaminoglycan. The dermal layer is designed with a controlled porosity and defined degradation rate that provides a scaffold for cellular invasion and capillary growth.
Integra® Wound Matrix (Thin) is an advanced wound care device comprised of collagen and glycosaminoglycan that maintains and supports a healing environment for wound management. Integra® Wound Matrix (Thin) contains 50% less collagen than Integra® Wound Matrix.
Kerecis® Omega3 MariGen is a fish-skin graft that is homologous to human skin and is used for tissue regeneration. The fish skin is a natural microbial barrier.
