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Cellular- and/or Tissue-Based Products

Cellular- and/or tissue-based products (CTPs) are types of wound dressings or coverings that support wound healing. There are multiple options for these products, including: non-viable cells, tissue-based: animal; non-viable cells, tissue-based: human; viable human cells, cultured in vitro: animal substrate; viable human cells, cultured in vitro: synthetic substrate; and viable human cells, non-cultured: intact tissue. 

In January 2026, new Final Rules regarding CTP/skin substitute application are scheduled to go into effect. Please consult your region’s Local Coverage Determination and/or your local payers’ guidelines for specific details on coverage and use specifications. Products listed in WoundSource may or may not be on the covered list under the new guidelines, so it is imperative that readers verify coverage policies, medical necessity requirements, and coding instructions for their desired product(s). See pages [XXX] for full disclaimer information.

Products

Corplex™

Corplex™ is a dehydrated human umbilical cord tissue allograft intended for homologous use. Provides a robust alternative to placental membrane allografts in a shelf-stable format.

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Cryo-Cord™

Cryo-Cord™ is a cryopreserved placental umbilical cord allograft that may be used as an anatomical barrier in numerous clinical applications. Retains the natural properties of placental tissue including nutrient-rich growth factors, cytokines, endogenous cells and Wharton's Jelly.

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Cytal™ Burn Matrix

Cytal™ Burn Matrix is a sterile, porcine-derived, naturally-occurring lyophilized extracellular matrix in sheet form that maintains and supports a healing environment for wound management.

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Cytal™ Wound Matrix (1-Layer, 2-Layer, 3-Layer, 6-Layer)

Cytal™ Wound Matrix is a sterile, porcine-derived, naturally-occurring lyophilized extracellular matrix in sheet form that maintains and supports a healing environment for wound management.

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DermACELL AWM®

DermACELL AWM® is a technologically advanced dermal matrix that is used in the treatment of chronic non-healing wounds such as diabetic foot ulcers.

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DermaPure® Decellularized Dermal Allograft

DermaPure® is 99% DNA-free decellularized dermal allograft with vascular-like channels and an intact ECM necessary to signal a cellular response to healing.

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Dermavest®

Dermavest® is a skin replacement derived from particularized, decellularized human placental tissue extracellular matrix.

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EPICORD® Dehydrated Human Umbilical Cord (DHUC) Allograft

EPICORD® Dehydrated Human Umbilical Cord (DHUC) Allograft is a placental-based tissue product that acts as a barrier and provides a protective environment to help support the healing process.

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EPICORD® EXPANDABLE Dehydrated Human Umbilical Cord (DHUC) Allograft

EPICORD® EXPANDABLE Dehydrated Human Umbilical Cord (DHUC) Allograft is a placental-based tissue product that acts as a barrier and provides a protective environment to help support the healing process. Expands from 6sq cm to 12sq cm.

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EPIEFFECT® Lyophilized Human Amnion Chorion Membrane (LHACM) Allograft

EPIEFFECT™ is a minimally manipulated, lyophilized, non-viable cellular allograft derived from human amniotic membrane.

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